منابع مشابه
Phenotypic switching: an opportunity to bacteria thrive
Bacteria in nature are “plagued“ by various unpredictable environmental stresses, being population diversity one of the strategies adopted to survive. Phenotypic switching is one of the evolution processes that causes commutation between phenotypic states. This phenomenon shows up as variation in colony morphology. Alterations in colony morphotype traits may reveal altered cellular basis phenot...
متن کاملPhospholipase A2 regulates eicosanoid class switching during inflammasome activation.
Initiation and resolution of inflammation are considered to be tightly connected processes. Lipoxins (LX) are proresolution lipid mediators that inhibit phlogistic neutrophil recruitment and promote wound-healing macrophage recruitment in humans via potent and specific signaling through the LXA4 receptor (ALX). One model of lipoxin biosynthesis involves sequential metabolism of arachidonic acid...
متن کاملEvolution of class switching
Antibody class switching emerged in evolutionary history when bony fish grew legs and became amphibians. On page 733, Barreto and colleagues show that the switch-inducing enzyme AID (activation-induced cytidine deaminase) is in working order in bony fish, suggesting that the evolution of the switch reaction had to wait for the acquisition of some other component. Bony fish produce antibodies bu...
متن کاملClass-switching neural network ensembles
This article investigates the properties of class-switching ensembles composed of neural networks and compares them to class-switching ensembles of decision trees and to standard ensemble learning methods, such as bagging and boosting. In a class-switching ensemble, each learner is constructed using a modified version of the training data. This modification consists in switching the class label...
متن کامل"Unequal opportunity": neighbourhood disadvantage and the chance to buy illegal drugs.
STUDY OBJECTIVES This study investigates whether subgroups of people living in disadvantaged neighbourhoods may be more likely to come into contact with drug dealers as compared with persons living in more advantaged areas, with due attention to male-female and race-ethnicity differences. DESIGN Standardised survey data collected using stratified, multistage area probability sampling. SETTI...
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ژورنال
عنوان ژورنال: Nature
سال: 2015
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature15209